Fluorescent in situ Hybridization (FISH)
Fluorescent in situ hybridization (FISH) is a technique for detecting and localizing DNA or RNA sequences within tissues, cells, and tumors. This technique takes advantage of fluorescent probes that only bind to chromosomal regions of interest or specific mRNAs. FISH also represents a key technology for DNA biomarker identification and quantification.
Applications:
- Chromosome mapping
- Identification of novel oncogenes
- Detection of genetic abnormalities (gene fusions, deletions, translocations)
- Research, diagnosis, and prognosis of genetic malignancies and tumors
- Patterns of gene expression studies
FISH Services:
- DNA FISH
- Oligo-based mRNA
- LNA based microRNAs
- Fusion Oncogenes: EML4/ALK…
